0435. Pressure-support ventilation compared to pressure-controlled ventilation in experimental emphysema

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0435. Pressure-support ventilation compared to pressure-controlled ventilation in experimental emphysema

Introduction Emphysema is characterized by irreversible enlargement of the airspaces distal to the terminal bronchiole, accompanied by destruction of their walls, and impairment of cardiac function. Acute exacerbation of emphysema leads to increased morbidity, mortality and, in some cases, requirement of invasive mechanical ventilation (MV). So far, no study has compared the impact of pressure-...

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Pressure-support improves lung protection and reduces cardiovascular dysfunction compared to pressure-controlled ventilation in experimental emphysema

Introduction Acute exacerbations of pulmonary emphysema lead to increased morbidity, mortality and, in some cases, requirement of invasive mechanical ventilation (MV) [1]. So far, no study has compared the biological impact of pressurecontrolled ventilation (PCV) versus pressure-support ventilation (PSV) in experimental emphysema. Our aims were to develop an elastase-induced emphysema model in ...

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Comparison of the effect of pressure support ventilation and volume assured pressure support ventilation on weaning patients off mechanical ventilation after cardiac surgery

Background: Weaning from mechanical ventilation in the intensive care unit is an important step in the treatment process. More patients in less than 6 hours after cardiac surgery can be separated from mechanical ventilation and extubated. However, 20-40% of patients after cardiac surgery, due to dysfunctional ventilator weaning response (DVWR), still remain under mechanical ventilation. Therefo...

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Comparison between effects of pressure support and pressure-controlled ventilation on lung and diaphragmatic damage in experimental emphysema

BACKGROUND In patients with emphysema, invasive mechanical ventilation settings should be adjusted to minimize hyperinflation while reducing respiratory effort and providing adequate gas exchange. We evaluated the impact of pressure-controlled ventilation (PCV) and pressure support ventilation (PSV) on pulmonary and diaphragmatic damage, as well as cardiac function, in experimental emphysema. ...

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Pressure-controlled ventilation and intrabronchial pressure during one-lung ventilation.

BACKGROUND Pressure-controlled ventilation (PCV) has been suggested to reduce peak airway pressure (P(peak)) and intrapulmonary shunt during one-lung ventilation (OLV) when compared with volume-controlled ventilation (VCV). At the same tidal volume (V(T)), the apparent difference in P(peak) is mainly related to the presence of a double-lumen tracheal tube. We tested the hypothesis that the decr...

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ژورنال

عنوان ژورنال: Intensive Care Medicine Experimental

سال: 2014

ISSN: 2197-425X

DOI: 10.1186/2197-425x-2-s1-p27